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1

Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil

Philip Seeman, Hong-Chang Guan, Hélène Hirbec

Journal:

Year:

2009

Language:

english

File:

PDF, 258 KB

english, 2009

2

Amphetamine sensitization elevates CaMKIIß mRNA

Rachel Greenstein, Gabriela Novak, Philip Seeman

Journal:

Year:

2007

Language:

english

File:

PDF, 190 KB

english, 2007

3

Dopamine receptors and the dopamine hypothesis of schizophrenia

Journal:

Year:

1987

Language:

english

File:

PDF, 2.52 MB

english, 1987

4

Relation between brain catecholamine receptors and dopaminergic stereotypy in rat strains

Daiga M. Helmeste, Philip Seeman, Donald V. Coscina

Journal:

European Journal of Pharmacology

Year:

1981

Language:

english

File:

PDF, 453 KB

english, 1981

5

Methylphenidate elevates resting dopamine which lowers the impulse-triggered release of dopamine: a hypothesis

Philip Seeman, Bertha Madras

Journal:

Behavioural Brain Research

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

6

Binding of 5H-Dibenzo[b,e][1,4]diazepine and Chiral 5H-Dibenzo[a,d]cycloheptene Analogs of Clozapine to Dopamine and Serotonin Receptors

Phillips, Shawn T., de Paulis, Tomas, Baron, Bruce M., Siegel, Barry W., Seeman, Philip, Van Tol, Hubert H. M., Guan, Hong-chang, Smith, Howard E.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.37 MB

english, 1994

7

Is schizophrenia a dopamine supersensitivity psychotic reaction?

Seeman, Mary V., Seeman, Philip

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2014

Language:

english

File:

PDF, 329 KB

english, 2014

8

Dopamine D2 Receptors as Treatment Targets in Schizophrenia

Journal:

Clinical Schizophrenia & Related Psychoses

Year:

2010

Language:

english

File:

PDF, 69 KB

english, 2010

9

Depression treatment by withdrawal of short-term low-dose antipsychotic, a proof-of-concept randomized double-blind study

Kennedy, Sidney H., Giacobbe, Peter, Placenza, Franca, Hudson, Craig J., Seeman, Philip, Seeman, Mary V.

Journal:

Journal of Affective Disorders

Year:

2014

Language:

english

File:

PDF, 537 KB

english, 2014

10

Characterization of brain D2 dopamine receptors

Lilly, Leslie, Davis, Alan, Fraser, Claire M., Seeman, Philip, Venter, J.Craig

Journal:

Neurochemistry International

Year:

1985

Language:

english

File:

PDF, 565 KB

english, 1985

11

On the Mechanism of the Nicotine-Induced Contracture of Skeletal Muscle

Thorpe, William R., Seeman, Philip

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1972

Language:

english

File:

PDF, 362 KB

english, 1972

12

A Study of Some “Test Dimensions” Conceptions

Seeman, William, Marks, Philip A.

Journal:

Journal of Projective Techniques

Year:

1962

Language:

english

File:

PDF, 361 KB

english, 1962

13

Reply: Atypical Antipsychotics Mechanisms of Action

Journal:

The Canadian Journal of Psychiatry

Year:

2003

Language:

english

File:

PDF, 52 KB

english, 2003

14

Dopamine D4 receptor variant in Africans, D4Valine194Glycine, is insensitive to dopamine and clozapine: Report of a homozygous individual

Liu, Ivy S. C., Seeman, Philip, Sanyal, Suparna, Ulpian, Carla, Rodgers-Johnson, Pamela E. B., Serjeant, Graham R., Van Tol, Hubert H. M.

Journal:

American Journal of Medical Genetics

Year:

1996

File:

PDF, 602 KB

1996

15

Dopamine D2-like sites in schizophrenia, but not in Alzheimer's, Huntington's, or control brains, for [3H]benzquinoline

Philip Seeman, Hong-Chang Guan, José Nobrega, Dilshad Jiwa, Rudolph Markstein, Ja-Hyun Balk, Roberto Picetti, Emiliana Borrelli, Hubert H.M. Van Tol

Journal:

Year:

1997

Language:

english

File:

PDF, 218 KB

english, 1997

16

The heterogeneity of some common psychiatric stereotypes

Philip A. Marks, William Seeman

Journal:

Journal of Clinical Psychology

Year:

1962

Language:

english

File:

PDF, 405 KB

english, 1962

17

A study of change in stereotype conceptions of psychological disorders

Philip A. Marks, William Seeman

Journal:

Journal of Clinical Psychology

Year:

1962

Language:

english

File:

PDF, 335 KB

english, 1962

18

Dopamine D4 receptor variant, D4GLYCINE194, in Africans, but not in Caucasians: No association with Schizophrenia

Philip Seeman, Carla Ulpian, Guy Chouinard, Hubert H. M. Van Tol, Hy Dwosh, Jeffrey A. Lieberman, Katherine Siminovitch, Ivy S. C. Liu, John Waye, P. Voruganti, Craig Hudson, Graham R. Serjeant, Arni

Journal:

American Journal of Medical Genetics Part A

Year:

1994

Language:

english

File:

PDF, 929 KB

english, 1994

19

Dopamine D2 receptor density remains constant in treated Parkinson's disease

Mark Guttman, Dr Philip Seeman, Gavin P. Reynolds, Peter Riederer, Kurt Jellinger, Wallace W. Tourtellotte

Journal:

Annals of Neurology

Year:

1986

Language:

english

File:

PDF, 780 KB

english, 1986

20

Dopamine receptor elevation in denervated tissues

Philip Seeman, Mark Guttman

Journal:

Annals of Neurology

Year:

1987

Language:

english

File:

PDF, 248 KB

english, 1987

21

Osteoporosis in rheumatoid arthritis

Philip N. Sambrook, Timothy D. Spector, Ego Seeman, Nicholas Bellamy, Russell R. C. Buchanan, David L. Duffy, Nicholas G. Martin, Richard Prince, Evan Owen, Alan J. Silman, John A. Eisman

Journal:

Arthritis & Rheumatism

Year:

1995

Language:

english

File:

PDF, 392 KB

english, 1995

22

Thermodynamic Analysis of Nylon Nucleic Acids

Yu Liu, Risheng Wang, Liang Ding, Ruojie Sha, Philip S. Lukeman, James W. Canary, Nadrian C. Seeman

Journal:

Year:

2008

Language:

english

File:

PDF, 333 KB

english, 2008

23

Selectivity of agonists and antagonists at D2dopamine receptors compared to D1 and S2receptors

Dr. Philip Seeman, Dimitri E. Grigoriadis, Hyman B. Niznik

Journal:

Drug Development Research

Year:

1986

Language:

english

File:

PDF, 332 KB

english, 1986

24

Brain region binding of the D2/3 agonist [11C]-(+)-PHNO and the D2/3 antagonist [11C]raclopride in healthy humans

Ariel Graff-Guerrero, Matthaeus Willeit, Nathalie Ginovart, David Mamo, Romina Mizrahi, Pablo Rusjan, Irina Vitcu, Philip Seeman, Alan A. Wilson, Shitij Kapur

Journal:

Human Brain Mapping

Year:

2008

Language:

english

File:

PDF, 412 KB

english, 2008

25

Age-related changes of β-adrenoceptors in spleen lymphocytes and cerebral cortex of NZB/BIN mice

Atsushi Kohno, Bernhard Cinader, Philip Seeman

Journal:

Immunology Letters

Year:

1986

Language:

english

File:

PDF, 209 KB

english, 1986

26

Dopamine D4-Like Receptor Elevation in Schizophrenia: Cloned D2 and D4 Receptors Cannot Be Discriminated by Raclopride Competition Against [3H]Nemonapride

Philip Seeman, Hubert H. M. Van Tol

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 317 KB

english, 1995

27

Amphetamine-sensitized animals show a marked increase in dopamine D2 high receptors occupied by endogenous dopamine, even in the absence of acute challenges

Philip Seeman, Teresa Tallerico, Françoise Ko, Catherine Tenn, Shitij Kapur

Journal:

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

28

Link between dopamine D1 and D2 receptors in rat and human striatal tissues

Philip Seeman, Teresa Tallerico

Journal:

Year:

2003

Language:

english

File:

PDF, 81 KB

english, 2003

29

Schizophrenia hippocampus has elevated expression of chondrex glycoprotein gene

Carmen Chung, Teresa Tallerico, Philip Seeman

Journal:

Year:

2003

Language:

english

File:

PDF, 236 KB

english, 2003

30

Anesthetics inhibit high-affinity states of dopamine D2 and other G-linked receptors

Philip Seeman, Shitij Kapur

Journal:

Year:

2003

Language:

english

File:

PDF, 119 KB

english, 2003

31

Dopamine displaces [3H]domperidone from high-affinity sites of the dopamine D2 receptor, but not [3H]raclopride or [3H]spiperone in isotonic medium: Implications for human positron emission tomography

Philip Seeman, Teresa Tallerico, Françoise Ko

Journal:

Year:

2003

Language:

english

File:

PDF, 119 KB

english, 2003

32

Alcohol-withdrawn animals have a prolonged increase in dopamine D2High receptors, reversed by general anesthesia: Relation to relapse?

Philip Seeman, Teresa Tallerico, Françoise Ko

Journal:

Year:

2004

Language:

english

File:

PDF, 143 KB

english, 2004

33

Antiparkinson concentrations of pramipexole and PHNO occupy dopamine D2high and D3high receptors

Philip Seeman, Françoise Ko, Matthäus Willeit, Patrick McCormick, Nathalie Ginovart

Journal:

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

34

Dopamine agonist action of phencyclidine

Philip Seeman, Mercedes Lasaga

Journal:

Year:

2005

Language:

english

File:

PDF, 59 KB

english, 2005

35

Psychosis pathways converge via D2High dopamine receptors

Philip Seeman, Johannes Schwarz, Jiang-Fan Chen, Henry Szechtman, Melissa Perreault, G. Stanley McKnight, John C. Roder, Rémi Quirion, Patricia Boksa, Lalit K. Srivastava, Kazuhiko Yanai, David Weinsh

Journal:

Year:

2006

Language:

english

File:

PDF, 509 KB

english, 2006

36

Radiosynthesis, ex vivo and in vivo evaluation of [11C]preclamol as a partial dopamine D2 agonist radioligand for positron emission tomography

Neil Vasdev, Sridhar Natesan, Laurent Galineau, Armando Garcia, Winston T. Stableford, Patrick McCormick, Philip Seeman, Sylvain Houle, Alan A. Wilson

Journal:

Year:

2006

Language:

english

File:

PDF, 108 KB

english, 2006

37

Antipsychotic pathway genes with expression altered in opposite direction by antipsychotics and amphetamine

Françoise Ko, Teresa Tallerico, Philip Seeman

Journal:

Year:

2006

Language:

english

File:

PDF, 166 KB

english, 2006

38

Dopamine D2 and D3 receptors in human putamen, caudate nucleus, and globus pallidus

Philip Seeman, Alan Wilson, Peter Gmeiner, Shitij Kapur

Journal:

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

39

Increased dopamine D2High receptors in amphetamine-sensitized rats, measured by the agonist [3H](+)PHNO

Philip Seeman, Patrick N. Mccormick, Shitij Kapur

Journal:

Year:

2007

Language:

english

File:

PDF, 206 KB

english, 2007

40

Consistent with dopamine supersensitivity, RGS9 expression is diminished in the amphetamine-treated animal model of schizophrenia and in postmortem schizophrenia brain

Philip Seeman, Françoise Ko, Elaine Jack, Rachel Greenstein, Brian Dean

Journal:

Year:

2007

Language:

english

File:

PDF, 152 KB

english, 2007

41

Elevated dopamine D2High receptors in α-1b-adrenoceptor knockout supersensitive mice

Jean-Pol Tassin, Yvette Torrens, Lucas Salomon, Christophe Lanteri, Philip Seeman

Journal:

Year:

2007

Language:

english

File:

PDF, 96 KB

english, 2007

42

Increased dopamine D2High receptors in knockouts of the dopamine transporter and the vesicular monoamine transporter may contribute to spontaneous hyperactivity and dopamine supersensitivity

Philip Seeman, Frank Scott Hall, George Uhl

Journal:

Year:

2007

Language:

english

File:

PDF, 96 KB

english, 2007

43

Antiparkinson therapeutic potencies correlate with their affinities at dopamine D2High receptors

Journal:

Year:

2007

Language:

english

File:

PDF, 318 KB

english, 2007

44

Memantine agonist action at dopamine D2High receptors

Philip Seeman, Carla Caruso, Mercedes Lasaga

Journal:

Year:

2008

Language:

english

File:

PDF, 116 KB

english, 2008

45

Dopamine D2High receptors moderately elevated by sertindole

Journal:

Year:

2008

Language:

english

File:

PDF, 176 KB

english, 2008

46

Increase of dopamine D2High receptors in the striatum of rats sensitized to caffeine motor effects

Nicola Simola, Micaela Morelli, Philip Seeman

Journal:

Year:

2008

Language:

english

File:

PDF, 79 KB

english, 2008

47

Dopamine partial agonist actions of the glutamate receptor agonists LY 354,740 and LY 379,268

Philip Seeman, Carla Caruso, Mercedes Lasaga

Journal:

Year:

2008

Language:

english

File:

PDF, 240 KB

english, 2008

48

Dopamine D2High receptors on intact cells

Journal:

Year:

2008

Language:

english

File:

PDF, 96 KB

english, 2008

49

Dopamine D2High receptors moderately elevated by bifeprunox and aripiprazole

Journal:

Year:

2008

Language:

english

File:

PDF, 311 KB

english, 2008

50

Phencyclidine and glutamate agonist LY379268 stimulate dopamine D2High receptors: D2 basis for schizophrenia

Philip Seeman, Hong-Chang Guan

Journal:

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008